Solution Architecture

Graph-temporal-causal fusion for explainable, equitable fertility intelligence.

Knowledge Graphs
Temporal Transformers
Causal Inference

Graph-Temporal-Causal Fusion

To solve the clinical crisis, Conceive engineers a multi-modal pipeline that unifies mechanistic biology, temporal tracking, and structural graph reasoning. Our computational architecture is built upon four foundational pillars that work in concert to deliver explainable, equitable, and clinically actionable fertility intelligence.

Four Foundational Pillars

The Core of Our Computational Architecture

01

Heterogeneous Knowledge Graphs

We map biological and behavioral realities by constructing a custom knowledge graph encoding the causal relationships between biomarkers (e.g., Estradiol, Progesterone), diagnoses (e.g., PCOS), treatments, and outcomes. Using Relational Graph Convolutional Networks (RGCNs), the system learns latent representations of these complex interactions.

RGCN Causal Mapping Biomarker Relationships
02

Temporal Transformer Encoding

Because fertility is a sequential, cycle-by-cycle process, we utilize time-series transformers to capture longitudinal dynamics and long-range dependencies across a patient's cycle history. This enables the model to understand patterns that span multiple cycles.

Time-Series Longitudinal Dynamics Long-Range Dependencies
03

Causal Inference & ITE

We do not stop at prediction. By layering a T-Learner meta-learner over a Structural Causal Model (SCM), our engine estimates counterfactuals. The system simulates how modifiable lifestyle factors or clinical treatments will directly uplift the individual's conception probability.

T-Learner Structural Causal Model Counterfactuals
04

Explainable AI (SHAP) & Fairness

Black-box medicine is unethical. Conceive utilizes SHAP to provide additive feature attributions, immediately highlighting which specific hormonal thresholds or lifestyle features are driving the prediction. Rigorous subgroup calibration audits ensure the model remains fair and reliable.

SHAP Explanations Feature Attribution Fairness Auditing

Technical Architecture

How It All Works Together

Input Layer
Demographic Data Hormonal Panels Medical Diagnoses Lifestyle Data
Processing Layer
Knowledge Graphs (RGCN) Temporal Transformers Causal Inference (T-Learner)
Output Layer
Conception Probability Individualized Treatment Effects SHAP Explanations Fairness Metrics
Deployment

API-First Deployment

Conceive is not a standalone academic dashboard; it is designed for enterprise scalability. The predictive engine is deployed as a privacy-preserving microservice via a robust FastAPI backend. This allows seamless integration into existing digital health ecosystems, fertility tracking applications, and electronic health records (EHR).

Microservice Architecture

Privacy-preserving FastAPI backend for seamless integration

Continuous Drift Monitoring

MLflow integration for real-time model performance tracking

Model Cards

Transparent documentation of model capabilities and limitations

Conceive Score API ● Online
POST /predict Get conception probability
POST /simulate Run counterfactual simulations
GET /explain Get SHAP explanations
GET /fairness Get fairness metrics

Ready to Integrate Conceive?

Join us in building the future of explainable, equitable fertility intelligence.